hrp0089pl6 | Personalized treatments using gut microbiome and clinical data | ESPE2018

Personalizing Treatments Using Microbiome and Clinical Data

Segal Eran

Accumulating evidence supports a causal role for the human gut microbiome in obesity, diabetes, metabolic disorders, cardiovascular disease, and numerous other conditions. I will present our research on the role of the human microbiome in health and disease, ultimately aimed at developing personalized medicine approaches that combine human genetics, microbiome, and nutrition. In one project, we tackled the subject of personalization of human nutrition, using a cohort of over 1...

hrp0095p1-497 | GH and IGFs | ESPE2022

Metabolomics profile of children with growth hormone deficiency

Shilo Smadar , Bar Noam , Halloun Rana , Cohen Michal , Rossman Hagai , Gal Shoshana , Oren Meirav , Malitsky Sergey , Itkin Maxim , Shahaf Nir , Lotan-Pompan Maya , Godneva Anastasia , Weinberger Adina , Tiosano Dov , Segal Eran

Background and Objectives: In recent years, a growing number of studies investigated the profile of serum metabolomics in health and disease. These studies have led to the discovery of novel biological biomarkers and causative agents for a variety of medical conditions. Here, we focused on profiling serum metabolites of children diagnosed with growth hormone deficiency (GHD).Methods: We conducted a prospective study and ...